Image Sample Data

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Science – April 10, 2020

The “spike” protein is the key target for vaccine and drug development efforts. "The K3 camera not only gave us great images…, it also prevented data collection from becoming a bottleneck, ultimately letting our team concentrate on getting the structure as quickly as possible” – UT Austin Lead Scientist

Distinct conformational states of SARS-CoV-2 spike protein

Solved with the BioQuantum™ K3^® System; Science – July 21, 2020

Cryo-EM structures of the COVID-19 spike protein in prefusion and postfusion conformations solved with Gatan equipment.

DPC maps of pyrochlore oxide specimen

Sample and data courtesy of J. Ciston, H. Brown, S. Hsu, LBNL.

Differential phase contrast (DPC) maps were calculated from a 4D STEM dataset acquired at atomic resolution from a pyrochlore oxide specimen using the GIF Continuum™ K3^® equipped with STEMx and the in-situ option. This energy-filtered 4D dataset included approximately 12,100 diffraction patterns and was collected in electron counting mode in <20 seconds.

Fast imaging enables live drift correction

With optional GPU, the K3 IS can automatically drift-correct single images during acquisition. An advanced algorithm handles low-signal, short-exposure frames from high-speed acquisition. The final image is a sum of the aligned frames.

Breakthrough K3 result

A 2.7 Å structure of the 20S Proteasome with the K3 camera and Elsa cryo-holder on a TF20. Data courtesy of Alexander Myasnikov, Michael Braunfeld, Yifan Cheng, and David Agard.

Better-Quality CL Modes of Operation for Analysis with Monarc

Better wavelength-filtered mapping, wavelength-resolved spectrum imaging, and wavelength-resolved hyperspectral data.

Artifact-free diffraction rings

$Artifact-free diffraction rings$

The Rio camera offers diffraction rings free from artifacts associated with CCD or other CMOS artifacts. Due to low noise floor, diffraction rings not usually visible in Au sample can be seen without artifacts from the central spot.

Choose the right FOV for your application

The Rio camera offers three cameras with both side and bottom mount. This allows you to pick the exact FOV that you need for your experiments.

Capture high-resolution detail with the largest FOV

There is no need to go to high magnification to resolve fine features. The Rio camera offers low noise with a high dynamic range.

Live drift correction and full resolution image display on the Rio camera

Image of gold sample captured with Rio 16 camera; 200 kV; image size: 4k x 4k; exposure time: 1 s.